Thyroid Updates by Professor Steven Boyages

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Thyroid hormone resistance gene

on January 15, 2013

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http://www.sciencealert.com.au/news/20131501-23962.html

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https://blogs.bcm.edu/2021/01/25/how-does-covid-19-impact-the-thyroid/ Main takeaways are: 1) pre-existing thyroid dysfunction does not lead to an increased COVID-19 infection rate or a worse prognosis during a COVID-19 infection, 2) COVID-19 can cause acute hypothyroidism via the non-thyroidal illness syndrome 3) COVID-19 can cause subacute hyperthyroidism, and 4) COVID-19 can cause overt thyrotoxicosis via direct inflammation of the thyroid. Long-term most acute thyroid dysfunction resolves once the patient has cleared the COVID-19 infection.

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NEW ORLEANS — Teprotumumab (Tepezza) works equally well in both older and younger patients with thyroid eye disease (TED) and regardless of TED duration, new data suggest. TED is an autoimmune disease characterized by orbital inflammation and expansion of fat and muscles around the eyes, resulting in proptosis, diplopia , pain, redness, and swelling. Many of the patients have Graves disease . In patients aged < 40 years, TED typically lacks restrictive myopathy, involves orbital fat expansion and proptosis with minimal to no periorbital inflammation or diplopia, and has low rates of dysthyroid optic neuropathy (type 1 disease). In contrast, in patients aged 40 years or older, TED often involves restrictive myopathy, along with extraocular muscle (EOM) enlargement and fibrosis, diplopia, and periorbital inflammation, and higher rates of dysthyroid optic neuropathy (type 2 disease). A small study published in 2023 s...

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Thyroid hormone resistance gene

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